Product Data Sheet
Dibenzothiophene-d8
Catalog No. A64105
Dibenzothiophene-d8 is a deuterium-labeled analogue of dibenzothiophene, serving as a stable isotope for research applications. This compound acts as a noncompetitive inhibitor of cytochrome P450 1A (CYP1A), demonstrating an inhibition of CYP1A-mediated EROD activity with a Km value of 0.592 μM. Additionally, dibenzothiophene-d8 interacts with the aryl hydrocarbon receptor (AHR) pathway and has been shown to enhance the embryotoxic effects of β-naphthoflavone. Its unique properties make it valuable for investigating the mechanisms of developmental toxicity in various organisms.
Chemical Information
| Catalog Num | A64105 |
|---|---|
| M. Wt | 192.31 |
| Formula | C12D8S |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 33262-29-2 |
| Synonyms | |
| SMILES | [2H]C1=C2C3=C([2H])C([2H])=C([2H])C([2H])=C3SC2=C([2H])C([2H])=C1[2H] |
Biological Activity
| Description | Dibenzothiophene-d8 is a deuterium-labeled analogue of dibenzothiophene, serving as a stable isotope for research applications. This compound acts as a noncompetitive inhibitor of cytochrome P450 1A (CYP1A), demonstrating an inhibition of CYP1A-mediated EROD activity with a Km value of 0.592 μM. Additionally, dibenzothiophene-d8 interacts with the aryl hydrocarbon receptor (AHR) pathway and has been shown to enhance the embryotoxic effects of β-naphthoflavone. Its unique properties make it valuable for investigating the mechanisms of developmental toxicity in various organisms. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
