Product Data Sheet

ISIS 329993

Catalog No. A64149

main product photo
ISIS 329993 is an antisense oligonucleotide designed to inhibit C-type lectin-like receptors (CTLRs). This compound has demonstrated significant biological activity in reducing C-reactive protein (CRP) levels, thereby improving clinical outcomes in rodent models of rheumatoid arthritis. It serves as a valuable research tool for investigating the therapeutic potential of CRP modulation in inflammatory diseases.
Chemical Information
Catalog NumA64149
M. Wt
Formula
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.827355-42-0
SynonymsISIS-CRPRx
SMILES[ISIS 329993]
Biological Activity
DescriptionISIS 329993 is an antisense oligonucleotide designed to inhibit C-type lectin-like receptors (CTLRs). This compound has demonstrated significant biological activity in reducing C-reactive protein (CRP) levels, thereby improving clinical outcomes in rodent models of rheumatoid arthritis. It serves as a valuable research tool for investigating the therapeutic potential of CRP modulation in inflammatory diseases.
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