Product Data Sheet
GBR-401
Catalog No. A64156
GBR-401 is a humanized anti-CD19 monoclonal antibody that targets CD19 with high affinity for FcγRIIIa. It exhibits potent cytotoxic activity against B-cell malignancies through mechanisms such as antibody-dependent cellular cytotoxicity (ADCC) and direct cell killing. GBR-401 is effective in depleting malignant B cells and has been shown to prolong survival in various xenograft models using severe combined immunodeficiency (SCID) mice, making it a valuable tool for cancer research and therapeutic development.
Chemical Information
| Catalog Num | A64156 |
|---|---|
| M. Wt | |
| Formula | |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 1931954-95-8 |
| Synonyms | |
| SMILES | N/A |
Biological Activity
| Description | GBR-401 is a humanized anti-CD19 monoclonal antibody that targets CD19 with high affinity for FcγRIIIa. It exhibits potent cytotoxic activity against B-cell malignancies through mechanisms such as antibody-dependent cellular cytotoxicity (ADCC) and direct cell killing. GBR-401 is effective in depleting malignant B cells and has been shown to prolong survival in various xenograft models using severe combined immunodeficiency (SCID) mice, making it a valuable tool for cancer research and therapeutic development. |
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RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
