Product Data Sheet

DDS5

Catalog No. A64172

main product photo
DDS5 is a selective CD28 inhibitor with an affinity (kd) of 175.57 µM, effectively disrupting the CD28-CD80 interaction with an IC50 value of 332 µM. This compound is instrumental in researching immune-mediated diseases, including inflammatory bowel disease and rheumatoid arthritis, enabling investigations into immune response modulation and therapeutic strategies.
Chemical Information
Catalog NumA64172
M. Wt305.42
FormulaC17H27N3O2
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.2871481-31-9
Synonyms
SMILESCOC1(C2)CCC2(C3=CN(CC4C(C)(C)CCO4)N=N3)CC1
Biological Activity
DescriptionDDS5 is a selective CD28 inhibitor with an affinity (kd) of 175.57 µM, effectively disrupting the CD28-CD80 interaction with an IC50 value of 332 µM. This compound is instrumental in researching immune-mediated diseases, including inflammatory bowel disease and rheumatoid arthritis, enabling investigations into immune response modulation and therapeutic strategies.
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