Product Data Sheet

Celecoxib-d3

Catalog No. A64298

main product photo
Celecoxib-d3 is a deuterium-labeled derivative of Celecoxib, a selective non-steroidal anti-inflammatory drug (NSAID) that specifically inhibits the COX-2 enzyme, exhibiting an IC50 value of 40 nM. This stable isotope is primarily utilized in pharmacokinetic studies and metabolic research to trace the kinetics and pathways of Celecoxib metabolism in biological systems. Celecoxib-d3 facilitates enhanced analytical sensitivity for investigating the drug’s biological effects and interactions.
Chemical Information
Catalog NumA64298
M. Wt384.39
FormulaC17H11D3F3N3O2S
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.544686-18-2
SynonymsSC 58635-d3
SMILESFC(F)(C1=NN(C2=CC=C(C=C2)S(N)(=O)=O)C(C3=CC=C(C=C3)C([2H])([2H])[2H])=C1)F
Biological Activity
DescriptionCelecoxib-d3 is a deuterium-labeled derivative of Celecoxib, a selective non-steroidal anti-inflammatory drug (NSAID) that specifically inhibits the COX-2 enzyme, exhibiting an IC50 value of 40 nM. This stable isotope is primarily utilized in pharmacokinetic studies and metabolic research to trace the kinetics and pathways of Celecoxib metabolism in biological systems. Celecoxib-d3 facilitates enhanced analytical sensitivity for investigating the drug’s biological effects and interactions.
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SHIPPING AND STORAGE
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