Product Data Sheet
Etoricoxib-d3
Catalog No. A64326
Etoricoxib-d3 is a deuterated form of Etoricoxib, a non-steroidal anti-inflammatory drug that selectively inhibits cyclooxygenase-2 (COX-2) with an IC50 value of 1.1 μM, while exhibiting negligible inhibition of COX-1 at 116 μM in human whole blood. This stable isotope-labeled compound is valuable for pharmacokinetic studies, metabolic profiling, and tracing studies in chemical research. Its unique isotopic signature enhances the detection and quantitation of Etoricoxib in biological samples.
Chemical Information
| Catalog Num | A64326 |
|---|---|
| M. Wt | 361.86 |
| Formula | C18H12D3ClN2O2S |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 850896-71-8 |
| Synonyms | MK-0663-d3; L-791456-d3 |
| SMILES | O=S(C1=CC=C(C2=CC(Cl)=CN=C2C3=CC=C(C)N=C3)C=C1)(C([2H])([2H])[2H])=O |
Biological Activity
| Description | Etoricoxib-d3 is a deuterated form of Etoricoxib, a non-steroidal anti-inflammatory drug that selectively inhibits cyclooxygenase-2 (COX-2) with an IC50 value of 1.1 μM, while exhibiting negligible inhibition of COX-1 at 116 μM in human whole blood. This stable isotope-labeled compound is valuable for pharmacokinetic studies, metabolic profiling, and tracing studies in chemical research. Its unique isotopic signature enhances the detection and quantitation of Etoricoxib in biological samples. |
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RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
