Product Data Sheet
2-Hydroxy Ibuprofen-d6
Catalog No. A64331
2-Hydroxy Ibuprofen-d6 is a stable isotope-labeled metabolite of Ibuprofen, which primarily inhibits cyclooxygenase enzymes COX-1 and COX-2, showing IC50 values of 13 μM and 370 μM, respectively. This reagent facilitates quantitative analysis in pharmacokinetic studies and metabolic profiling, allowing researchers to accurately track the metabolic pathways of Ibuprofen and its derivatives. Its stable isotope labeling enhances the sensitivity and specificity of various analytical techniques, including mass spectrometry.
Chemical Information
| Catalog Num | A64331 |
|---|---|
| M. Wt | 228.32 |
| Formula | C13H12D6O3 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 1217055-71-4 |
| Synonyms | (±)-2-Hydroxy Ibuprofen-d6 |
| SMILES | [2H]C([2H])([2H])C(C([2H])([2H])[2H])(O)CC1=CC=C(C=C1)C(C)C(O)=O |
Biological Activity
| Description | 2-Hydroxy Ibuprofen-d6 is a stable isotope-labeled metabolite of Ibuprofen, which primarily inhibits cyclooxygenase enzymes COX-1 and COX-2, showing IC50 values of 13 μM and 370 μM, respectively. This reagent facilitates quantitative analysis in pharmacokinetic studies and metabolic profiling, allowing researchers to accurately track the metabolic pathways of Ibuprofen and its derivatives. Its stable isotope labeling enhances the sensitivity and specificity of various analytical techniques, including mass spectrometry. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
