Product Data Sheet
Phenylbutazone-d9
Catalog No. A64333
Phenylbutazone-d9 is a deuterium-labeled analog of Phenylbutazone, a potent nonsteroidal anti-inflammatory drug (NSAID) that functions as a reducing cofactor for the peroxidase activity of prostaglandin H synthase (PHS). This compound exhibits significant hepatotoxicity and is known to induce the expression of muscle blind-like protein 1 (MBNL1). Phenylbutazone-d9 is valuable for research applications focused on ankylosing spondylitis and related inflammatory conditions, as well as for studying drug metabolism and pharmacokinetics involving stable isotope labeling.
Chemical Information
| Catalog Num | A64333 |
|---|---|
| M. Wt | 317.43 |
| Formula | C19H11D9N2O2 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 1189479-75-1 |
| Synonyms | |
| SMILES | O=C1N(C2=CC=CC=C2)N(C3=CC=CC=C3)C(C1C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])[2H])=O |
Biological Activity
| Description | Phenylbutazone-d9 is a deuterium-labeled analog of Phenylbutazone, a potent nonsteroidal anti-inflammatory drug (NSAID) that functions as a reducing cofactor for the peroxidase activity of prostaglandin H synthase (PHS). This compound exhibits significant hepatotoxicity and is known to induce the expression of muscle blind-like protein 1 (MBNL1). Phenylbutazone-d9 is valuable for research applications focused on ankylosing spondylitis and related inflammatory conditions, as well as for studying drug metabolism and pharmacokinetics involving stable isotope labeling. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
