Product Data Sheet

Phenacetin-13C

Catalog No. A64367

main product photo
Phenacetin-13C is a stable isotope-labeled derivative of Phenacetin, a non-opioid analgesic and antipyretic agent that selectively inhibits COX-3 enzymes. This compound serves as a valuable tool in pharmacokinetic studies and metabolic profiling, particularly as a probe for cytochrome P450 enzymes CYP1A2 in human liver microsomes and rat models. Its utility in assessing drug metabolism and disposition makes it a critical reagent for researchers investigating analgesic mechanisms and metabolic pathways.
Chemical Information
Catalog NumA64367
M. Wt180.21
FormulaC913CH13NO2
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.72156-72-0
Synonyms
SMILESCC(NC1=CC=C(C=C1)O[13CH2]C)=O
Biological Activity
DescriptionPhenacetin-13C is a stable isotope-labeled derivative of Phenacetin, a non-opioid analgesic and antipyretic agent that selectively inhibits COX-3 enzymes. This compound serves as a valuable tool in pharmacokinetic studies and metabolic profiling, particularly as a probe for cytochrome P450 enzymes CYP1A2 in human liver microsomes and rat models. Its utility in assessing drug metabolism and disposition makes it a critical reagent for researchers investigating analgesic mechanisms and metabolic pathways.
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