Product Data Sheet
Valdecoxib-13C2,15N
Catalog No. A64379
Valdecoxib-13C2,15N is a stable isotope-labeled derivative of Valdecoxib, a selective and potent inhibitor of cyclooxygenase-2 (COX-2) with an IC50 of 5 nM, while displaying significantly lower activity against COX-1 (IC50 of 140 µM). This compound is utilized in pharmacological research to investigate the mechanisms of pain and inflammation, particularly in studies related to arthritis. The incorporation of stable isotopes facilitates advanced analytical techniques such as mass spectrometry in drug metabolism and pharmacokinetics research.
Chemical Information
| Catalog Num | A64379 |
|---|---|
| M. Wt | 317.34 |
| Formula | C1413C2H14N15NO3S |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 1189428-23-6 |
| Synonyms | SC 65872-13C2,15N |
| SMILES | [13CH3][13C](O[15N]=C1C2=CC=CC=C2)=C1C3=CC=C(S(N)(=O)=O)C=C3 |
Biological Activity
| Description | Valdecoxib-13C2,15N is a stable isotope-labeled derivative of Valdecoxib, a selective and potent inhibitor of cyclooxygenase-2 (COX-2) with an IC50 of 5 nM, while displaying significantly lower activity against COX-1 (IC50 of 140 µM). This compound is utilized in pharmacological research to investigate the mechanisms of pain and inflammation, particularly in studies related to arthritis. The incorporation of stable isotopes facilitates advanced analytical techniques such as mass spectrometry in drug metabolism and pharmacokinetics research. |
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RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
