Diclofenac amide
Catalog No. A64422

Diclofenac amide is a prodrug that functions as an oral inhibitor of cyclooxygenase-1 and -2 (COX-1/2), effectively reducing the synthesis of prostaglandins and thromboxanes. This compound demonstrates significant anti-inflammatory activity in the carrageenan-induced rat paw edema model while preserving gastric integrity, making it a valuable tool for studying inflammation and pain mechanisms. Its favorable safety profile and effectiveness position it as a promising candidate in pharmacological research.
Chemical Information
| Catalog Num | A64422 |
|---|---|
| M. Wt | 278.14 |
| Formula | C14H9Cl2NO |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 15362-40-0 |
| Synonyms | |
| SMILES | O=C1N(C2=C(Cl)C=CC=C2Cl)C3=C(C=CC=C3)C1 |
Biological Activity
| Description | Diclofenac amide is a prodrug that functions as an oral inhibitor of cyclooxygenase-1 and -2 (COX-1/2), effectively reducing the synthesis of prostaglandins and thromboxanes. This compound demonstrates significant anti-inflammatory activity in the carrageenan-induced rat paw edema model while preserving gastric integrity, making it a valuable tool for studying inflammation and pain mechanisms. Its favorable safety profile and effectiveness position it as a promising candidate in pharmacological research. |
|---|
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Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.


