Product Data Sheet

Anti-inflammatory agent 8

Catalog No. A64450

main product photo
Anti-inflammatory agent 8 is a tilomisole-based benzimidazothiazole derivative targeting the COX-2 enzyme with enhanced selectivity over COX-1, exhibiting an IC50 of 0.09 nM. This compound demonstrates significant anti-inflammatory activity, making it a valuable tool for research into mechanisms of inflammation and related pathophysiological conditions. Its oral bioavailability supports its utility in in vivo studies.
Chemical Information
Catalog NumA64450
M. Wt381.47
FormulaC18H15N5OS2
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.1103920-19-9
Synonyms
SMILESO=C(C1=C(C)N2C3=CC=CC=C3N=C2S1)NNC(NC4=CC=CC=C4)=S
Biological Activity
DescriptionAnti-inflammatory agent 8 is a tilomisole-based benzimidazothiazole derivative targeting the COX-2 enzyme with enhanced selectivity over COX-1, exhibiting an IC50 of 0.09 nM. This compound demonstrates significant anti-inflammatory activity, making it a valuable tool for research into mechanisms of inflammation and related pathophysiological conditions. Its oral bioavailability supports its utility in in vivo studies.
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