Product Data Sheet

COX-2-IN-23

Catalog No. A64452

main product photo
COX-2-IN-23 is a selective inhibitor of cyclooxygenase-2 (COX-2), exhibiting IC50 values of 0.28 μM for COX-2 and 20.14 μM for COX-1. This compound demonstrates significant anti-inflammatory activity while maintaining a low ulcerogenic profile, making it suitable for research applications focused on inflammation and pain modulation. Its selectivity and efficacy position it as a valuable tool in the study of inflammatory pathways.
Chemical Information
Catalog NumA64452
M. Wt495.62
FormulaC24H25N5O3S2
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.2417995-08-3
Synonyms
SMILESO=S(C1=CC(C(N2C3=CC=CC=C3)=NNC2=S)=CC(NCCCC)=C1OC4=CC=CC=C4)(N)=O
Biological Activity
DescriptionCOX-2-IN-23 is a selective inhibitor of cyclooxygenase-2 (COX-2), exhibiting IC50 values of 0.28 μM for COX-2 and 20.14 μM for COX-1. This compound demonstrates significant anti-inflammatory activity while maintaining a low ulcerogenic profile, making it suitable for research applications focused on inflammation and pain modulation. Its selectivity and efficacy position it as a valuable tool in the study of inflammatory pathways.
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