Product Data Sheet

Mefenamic acid-13C6

Catalog No. A64468

main product photo
Mefenamic acid-13C6 is a stable isotope-labeled derivative of Mefenamic acid, a non-steroidal anti-inflammatory drug (NSAID) that penetrates the blood-brain barrier. It functions as a competitive inhibitor of human cyclooxygenase-1 (hCOX-1) and human cyclooxygenase-2 (hCOX-2), with reported IC50 values of 40 nM and 3 μM, respectively. This reagent is valuable for metabolic studies and pharmacokinetic research involving the behavior of Mefenamic acid in biological systems.
Chemical Information
Catalog NumA64468
M. Wt247.24
FormulaC913C6H15NO2
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.1325559-19-0
Synonyms
SMILESOC([13C]([13CH]=[13CH][13CH]=[13CH]1)=[13C]1NC2=C(C(C)=CC=C2)C)=O
Biological Activity
DescriptionMefenamic acid-13C6 is a stable isotope-labeled derivative of Mefenamic acid, a non-steroidal anti-inflammatory drug (NSAID) that penetrates the blood-brain barrier. It functions as a competitive inhibitor of human cyclooxygenase-1 (hCOX-1) and human cyclooxygenase-2 (hCOX-2), with reported IC50 values of 40 nM and 3 μM, respectively. This reagent is valuable for metabolic studies and pharmacokinetic research involving the behavior of Mefenamic acid in biological systems.
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