Product Data Sheet
Anti-inflammatory agent 56
Catalog No. A64477
Anti-inflammatory agent 56 is a selective COX-2 inhibitor with an IC50 of 0.54 μM. It demonstrates significant anti-inflammatory and antioxidant properties, effectively reducing oxidative stress-induced cell death. By inhibiting key targets such as Keap1, COX-2, and iNOS, this compound mitigates neuroinflammation and oxidative stress. Furthermore, it exhibits low acute toxicity in murine models, with an LD50 of 1000 mg/kg, making it a valuable tool for research in inflammation and neuroprotection.
Chemical Information
| Catalog Num | A64477 |
|---|---|
| M. Wt | 476.43 |
| Formula | C21H15F3N4O4S |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 2413127-32-7 |
| Synonyms | |
| SMILES | O=S(N)(C1=CC=C(N2N=C(C3=C(O)C=C(C(F)(F)F)C=C3)N=C2C4=C(O)C=CC=C4)C=C1)=O |
Biological Activity
| Description | Anti-inflammatory agent 56 is a selective COX-2 inhibitor with an IC50 of 0.54 μM. It demonstrates significant anti-inflammatory and antioxidant properties, effectively reducing oxidative stress-induced cell death. By inhibiting key targets such as Keap1, COX-2, and iNOS, this compound mitigates neuroinflammation and oxidative stress. Furthermore, it exhibits low acute toxicity in murine models, with an LD50 of 1000 mg/kg, making it a valuable tool for research in inflammation and neuroprotection. |
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RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
