Product Data Sheet

COX-2-IN-24

Catalog No. A64510

main product photo
COX-2-IN-24 is an orally active inhibitor of cyclooxygenase-2 (COX-2) with an IC50 value of 0.17 μM. This compound exhibits significant anti-inflammatory properties while demonstrating low ulcerogenic activities, making it suitable for research on inflammatory diseases and pain management. Its selective inhibition of COX-2 provides valuable insights into the mechanisms of inflammation and the development of therapeutic strategies.
Chemical Information
Catalog NumA64510
M. Wt574.51
FormulaC24H24BrN5O3S2
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.2417995-10-7
Synonyms
SMILESO=S(C1=CC(C(N2C3=CC=C(Br)C=C3)=NNC2=S)=CC(NCCCC)=C1OC4=CC=CC=C4)(N)=O
Biological Activity
DescriptionCOX-2-IN-24 is an orally active inhibitor of cyclooxygenase-2 (COX-2) with an IC50 value of 0.17 μM. This compound exhibits significant anti-inflammatory properties while demonstrating low ulcerogenic activities, making it suitable for research on inflammatory diseases and pain management. Its selective inhibition of COX-2 provides valuable insights into the mechanisms of inflammation and the development of therapeutic strategies.
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