Product Data Sheet
Timegadine hydrochloride
Catalog No. A64514
Timegadine hydrochloride is a selective inhibitor of cyclooxygenase (COX) and lipoxygenase, playing a significant role in inflammatory processes. It demonstrates potent COX inhibition in washed rabbit platelets and rat brain, with IC50 values of 5 nM and 20 μM, respectively. Additionally, Timegadine hydrochloride effectively inhibits lipoxygenase in equine and washed rabbit platelets with an IC50 of 100 μM. This compound is of interest for research applications focusing on anti-arthritis activity and other inflammatory conditions.
Chemical Information
| Catalog Num | A64514 |
|---|---|
| M. Wt | 401.96 |
| Formula | C20H24ClN5S |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 71080-06-3 |
| Synonyms | SR1368 hydrochloride |
| SMILES | CC1=NC2=C(C(/N=C(NC3CCCCC3)/NC4=NC=CS4)=C1)C=CC=C2.Cl |
Biological Activity
| Description | Timegadine hydrochloride is a selective inhibitor of cyclooxygenase (COX) and lipoxygenase, playing a significant role in inflammatory processes. It demonstrates potent COX inhibition in washed rabbit platelets and rat brain, with IC50 values of 5 nM and 20 μM, respectively. Additionally, Timegadine hydrochloride effectively inhibits lipoxygenase in equine and washed rabbit platelets with an IC50 of 100 μM. This compound is of interest for research applications focusing on anti-arthritis activity and other inflammatory conditions. |
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RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
