Product Data Sheet
Firocoxib-d4
Catalog No. A64528
Firocoxib-d4 is a deuterium-labeled derivative of Firocoxib, acting primarily as a selective inhibitor of cyclooxygenase-2 (COX-2). With an IC50 value of 0.13 μM, Firocoxib demonstrates a notable selectivity, being 58-fold more potent against COX-2 compared to COX-1 (IC50 of 7.5 μM). This compound is primarily utilized in research to investigate COX-2's role in inflammation and associated therapeutic targets. Its stable isotope labeling allows for advanced studies in pharmacokinetics and metabolism in biological systems.
Chemical Information
| Catalog Num | A64528 |
|---|---|
| M. Wt | 340.43 |
| Formula | C17H16D4O5S |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 1325700-11-5 |
| Synonyms | |
| SMILES | O(CC1C(C1([2H])[2H])([2H])[2H])C2=C(C(C)(C)OC2=O)C3=CC=C(S(C)(=O)=O)C=C3 |
Biological Activity
| Description | Firocoxib-d4 is a deuterium-labeled derivative of Firocoxib, acting primarily as a selective inhibitor of cyclooxygenase-2 (COX-2). With an IC50 value of 0.13 μM, Firocoxib demonstrates a notable selectivity, being 58-fold more potent against COX-2 compared to COX-1 (IC50 of 7.5 μM). This compound is primarily utilized in research to investigate COX-2's role in inflammation and associated therapeutic targets. Its stable isotope labeling allows for advanced studies in pharmacokinetics and metabolism in biological systems. |
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RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
