Product Data Sheet

COX-1/2-IN-6

Catalog No. A64541

main product photo
COX-1/2-IN-6 is a potent dual inhibitor of cyclooxygenase-1 (COX-1) and cyclooxygenase-2 (COX-2), exhibiting IC50 values of 68 nM and 91 nM, respectively. This compound is valuable for studying inflammatory diseases by effectively modulating the COX enzymatic pathways involved in prostaglandin synthesis. Its inhibition profile makes it suitable for research on pain management and inflammatory-related conditions.
Chemical Information
Catalog NumA64541
M. Wt363.41
FormulaC22H21NO4
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.327024-84-0
Synonyms
SMILESO=C(C1=C(C)N(CC(O)=O)C(C2=CC=C(C3=CC=CC=C3)C=C2)=C1)OCC
Biological Activity
DescriptionCOX-1/2-IN-6 is a potent dual inhibitor of cyclooxygenase-1 (COX-1) and cyclooxygenase-2 (COX-2), exhibiting IC50 values of 68 nM and 91 nM, respectively. This compound is valuable for studying inflammatory diseases by effectively modulating the COX enzymatic pathways involved in prostaglandin synthesis. Its inhibition profile makes it suitable for research on pain management and inflammatory-related conditions.
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