Product Data Sheet
QKY-613
Catalog No. A64590
QKY-613 is a cGAS activator designed to enhance immune surveillance through nucleic acid modification pathways. As a prodrug, QKY-613 promotes the incorporation of 6mdA (N6-methyldeoxyadenosine) into viral DNA, which increases the phase separation potential and activates cGAS. In studies using virus-infected mouse models, QKY-613 demonstrated a significant reduction in mortality among aged mice. This compound is valuable for research investigating nucleic acid modification mechanisms and their role in immune response enhancement.
Chemical Information
| Catalog Num | A64590 |
|---|---|
| M. Wt | 582.54 |
| Formula | C27H31N6O7P |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 2646682-38-2 |
| Synonyms | |
| SMILES | O[C@H]1C[C@H](N(C=N2)C3=C2C(NC)=NC=N3)O[C@@H]1COP(OC4=CC=CC=C4)(N[C@H](C(OCC5=CC=CC=C5)=O)C)=O |
Biological Activity
| Description | QKY-613 is a cGAS activator designed to enhance immune surveillance through nucleic acid modification pathways. As a prodrug, QKY-613 promotes the incorporation of 6mdA (N6-methyldeoxyadenosine) into viral DNA, which increases the phase separation potential and activates cGAS. In studies using virus-infected mouse models, QKY-613 demonstrated a significant reduction in mortality among aged mice. This compound is valuable for research investigating nucleic acid modification mechanisms and their role in immune response enhancement. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
