Product Data Sheet

CypD-IN-29

Catalog No. A64601

main product photo
CypD-IN-29 is a selective inhibitor of Cyclophilin D (CypD), with a key dissociation constant (KD) of 88.2 nM. By targeting CypD, this compound interferes with its interaction with β-amyloid protein in mitochondrial environments, thereby mitigating the formation of mitochondrial permeability transition pores (mPTP). CypD-IN-29 is suited for research focused on Alzheimer's disease mechanisms and mitochondrial dysfunction in neuronal cells.
Chemical Information
Catalog NumA64601
M. Wt485.53
FormulaC26H20FN5O2S
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.1115335-95-9
Synonyms
SMILESO=C(NCC1=CC=C(F)C=C1)C2=CC=CC(N3C=CN=C3SCC(NC4=CC=CC=C4C#N)=O)=C2
Biological Activity
DescriptionCypD-IN-29 is a selective inhibitor of Cyclophilin D (CypD), with a key dissociation constant (KD) of 88.2 nM. By targeting CypD, this compound interferes with its interaction with β-amyloid protein in mitochondrial environments, thereby mitigating the formation of mitochondrial permeability transition pores (mPTP). CypD-IN-29 is suited for research focused on Alzheimer's disease mechanisms and mitochondrial dysfunction in neuronal cells.
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