Product Data Sheet

GB1908

Catalog No. A64680

main product photo
GB1908 is a selective oral inhibitor of galectin-1, demonstrating Ki values of 57 nM and 72 nM for human and mouse galectin-1, respectively. This compound exhibits over 50-fold selectivity for galectin-1 compared to galectin-3. GB1908 serves as a valuable tool in the investigation of lung cancer and related therapeutic strategies, facilitating research into the role of galectin-1 in tumor progression and immune modulation.
Chemical Information
Catalog NumA64680
M. Wt505.40
FormulaC18H18Cl2N4O5S2
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.2573135-31-4
Synonyms
SMILESClC1=CC(S[C@H]2O[C@H](CO)[C@H](O)[C@H](N3C=C(C4=CSC(O)=N4)N=N3)[C@H]2OC)=CC=C1Cl
Biological Activity
DescriptionGB1908 is a selective oral inhibitor of galectin-1, demonstrating Ki values of 57 nM and 72 nM for human and mouse galectin-1, respectively. This compound exhibits over 50-fold selectivity for galectin-1 compared to galectin-3. GB1908 serves as a valuable tool in the investigation of lung cancer and related therapeutic strategies, facilitating research into the role of galectin-1 in tumor progression and immune modulation.
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SHIPPING AND STORAGE
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