Product Data Sheet
Medrysone
Catalog No. A64710
Medrysone, also known as 6α-Methyl-11β-hydroxyprogesterone, functions as a STAT6 modulator with significant implications for macrophage polarization. This compound enhances IL-4-induced STAT6 activation, leading to increased expression of M2 macrophage markers and elevated secretion of pro-angiogenic factors such as VEGF and CCL2. Additionally, Medrysone promotes the migratory capacity of M2-like macrophages towards endothelial cells, thereby facilitating tissue repair processes. Its efficacy in regulating macrophage polarization makes it a valuable tool for research on corneal injury and wound healing applications.
Chemical Information
| Catalog Num | A64710 |
|---|---|
| M. Wt | 344.49 |
| Formula | C22H32O3 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 2668-66-8 |
| Synonyms | HMS; 6α-Methyl-11β-hydroxyprogesterone |
| SMILES | CC([C@H]1CC[C@@]2([H])[C@]3([H])C[C@H](C)C4=CC(CC[C@]4(C)[C@@]3([H])[C@@H](O)C[C@]12C)=O)=O |
Biological Activity
| Description | Medrysone, also known as 6α-Methyl-11β-hydroxyprogesterone, functions as a STAT6 modulator with significant implications for macrophage polarization. This compound enhances IL-4-induced STAT6 activation, leading to increased expression of M2 macrophage markers and elevated secretion of pro-angiogenic factors such as VEGF and CCL2. Additionally, Medrysone promotes the migratory capacity of M2-like macrophages towards endothelial cells, thereby facilitating tissue repair processes. Its efficacy in regulating macrophage polarization makes it a valuable tool for research on corneal injury and wound healing applications. |
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RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
