Fluticasone
Catalog No. A64711

Fluticasone is a synthetic corticosteroid that acts as an agonist of the Smoothened (Smo) receptor, with an IC50 value of 99 nM. This compound activates Hedgehog signaling pathways, promoting the proliferation of primary neuronal stem or precursor cells. Fluticasone is utilized in respiratory research and can provide insights into mechanisms related to cell growth and differentiation within the context of Hedgehog signaling.
Chemical Information
| Catalog Num | A64711 |
|---|---|
| M. Wt | 444.51 |
| Formula | C22H27F3O4S |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 90566-53-3 |
| Synonyms | |
| SMILES | C[C@]([C@](O)1C(SCF)=O)(C[C@@H]2O)[C@](C[C@H]1C)([H])[C@@](C[C@@H]3F)([H])[C@]2([C@](C3=CC4=O)(C=C4)C)F |
Biological Activity
| Description | Fluticasone is a synthetic corticosteroid that acts as an agonist of the Smoothened (Smo) receptor, with an IC50 value of 99 nM. This compound activates Hedgehog signaling pathways, promoting the proliferation of primary neuronal stem or precursor cells. Fluticasone is utilized in respiratory research and can provide insights into mechanisms related to cell growth and differentiation within the context of Hedgehog signaling. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.


