Product Data Sheet

Dazucorilant

Catalog No. A64719

main product photo
Dazucorilant is a selective and high-affinity non-steroidal modulator of the glucocorticoid receptor (GR), demonstrating a Ki value of less than 1 nM in vitro. This compound is primarily utilized in research focused on neurological disorders, offering a valuable tool to investigate GR-related mechanisms and therapeutic potentials in conditions influenced by glucocorticoid signaling.
Chemical Information
Catalog NumA64719
M. Wt582.57
FormulaC29H22F4N4O3S
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.1496508-34-9
SynonymsCORT113176
SMILESO=C(C1=CC=CC=N1)[C@@]23C(CCN(C3)S(=O)(C4=CC=C(C=C4)C(F)(F)F)=O)=CC5=C(C=NN5C6=CC=C(C=C6)F)C2
Biological Activity
DescriptionDazucorilant is a selective and high-affinity non-steroidal modulator of the glucocorticoid receptor (GR), demonstrating a Ki value of less than 1 nM in vitro. This compound is primarily utilized in research focused on neurological disorders, offering a valuable tool to investigate GR-related mechanisms and therapeutic potentials in conditions influenced by glucocorticoid signaling.
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SHIPPING AND STORAGE
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