Product Data Sheet

GSK866

Catalog No. A64730

main product photo
GSK866, also known as (S)-GSK47866A, is a selective agonist of the glucocorticoid receptor, exhibiting an IC50 of 4.6 nM. This compound is utilized in research to explore the biological effects mediated by glucocorticoid receptor activation, including anti-inflammatory responses and cell signaling pathways. Its potency makes GSK866 a valuable tool in studies aimed at understanding the therapeutic potential of glucocorticoids in various diseases.
Chemical Information
Catalog NumA64730
M. Wt562.34
FormulaC23H21Cl2F4N5O3
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.1991970-93-4
Synonyms(S)-GSK47866A
SMILESNC1=C(C(NC[C@](C(F)(F)F)(O)CN(CC)C(C2=C(C=CC=C2Cl)Cl)=O)=O)C=NN1C3=CC=C(C=C3)F
Biological Activity
DescriptionGSK866, also known as (S)-GSK47866A, is a selective agonist of the glucocorticoid receptor, exhibiting an IC50 of 4.6 nM. This compound is utilized in research to explore the biological effects mediated by glucocorticoid receptor activation, including anti-inflammatory responses and cell signaling pathways. Its potency makes GSK866 a valuable tool in studies aimed at understanding the therapeutic potential of glucocorticoids in various diseases.
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SHIPPING AND STORAGE
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