Product Data Sheet
J9
Catalog No. A64777
J9 is a small molecule that acts as a Dexamethasone resistance reverser in T-cell acute lymphoblastic leukemia. This compound selectively induces cell lethality in CUTLL1 cells when administered alongside Dexamethasone, demonstrating an effective inhibition of cell growth with an EC50 value of 28 μM. J9 is a valuable tool for exploring mechanisms underlying glucocorticoid resistance and enhancing therapeutic strategies in hematological malignancies.
Chemical Information
| Catalog Num | A64777 |
|---|---|
| M. Wt | 212.25 |
| Formula | C12H12N4 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 947018-15-7 |
| Synonyms | |
| SMILES | NC1=NC=C(C2=CC=NC=C2)C(C3CC3)=N1 |
Biological Activity
| Description | J9 is a small molecule that acts as a Dexamethasone resistance reverser in T-cell acute lymphoblastic leukemia. This compound selectively induces cell lethality in CUTLL1 cells when administered alongside Dexamethasone, demonstrating an effective inhibition of cell growth with an EC50 value of 28 μM. J9 is a valuable tool for exploring mechanisms underlying glucocorticoid resistance and enhancing therapeutic strategies in hematological malignancies. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
