Product Data Sheet
LY2623091
Catalog No. A64806
LY2623091 is a potent glucocorticoid receptor antagonist known for its role in modulating mineralocorticoid signaling. This compound demonstrates significant potential in the treatment of refractory hypertension by inhibiting the action of glucocorticoids, thereby addressing hypertension mechanisms. Additionally, LY2623091 exhibits CYP3A4-dependent clearance, presenting possibilities for synergistic therapeutic strategies when used in conjunction with CYP3A4 inhibitors in research applications.
Chemical Information
| Catalog Num | A64806 |
|---|---|
| M. Wt | 527.59 |
| Formula | C30H30FN5O3 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 1162264-07-4 |
| Synonyms | |
| SMILES | FC1=CC=C(C(OCC2=CC=CC=C/32)=C1)C3=C\C4=CC=C(N([C@H](C)CN5CCOCC5)C(NC(N)=O)=N6)C6=C4 |
Biological Activity
| Description | LY2623091 is a potent glucocorticoid receptor antagonist known for its role in modulating mineralocorticoid signaling. This compound demonstrates significant potential in the treatment of refractory hypertension by inhibiting the action of glucocorticoids, thereby addressing hypertension mechanisms. Additionally, LY2623091 exhibits CYP3A4-dependent clearance, presenting possibilities for synergistic therapeutic strategies when used in conjunction with CYP3A4 inhibitors in research applications. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
