Product Data Sheet

Win 45164

Catalog No. A64822

main product photo
Win 45164 is an orally active ligand of the glucocorticoid receptor, primarily known for its inhibitory effects on the pituitary-adrenal axis. It promotes liver glycogen deposition and thymus involution in adrenalectomized male rats, highlighting its physiological relevance. Additionally, Win 45164 exhibits significant anti-inflammatory properties, making it a valuable tool for research in inflammatory and neurological diseases.
Chemical Information
Catalog NumA64822
M. Wt418.50
FormulaC26H27FN2O2
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.83880-39-1
Synonyms
SMILESO=C(C1CC=C2C(C1C(C)=O)CCC3=CC4=C(CC32C)C=NN4C5=CC=C(C=C5)F)C
Biological Activity
DescriptionWin 45164 is an orally active ligand of the glucocorticoid receptor, primarily known for its inhibitory effects on the pituitary-adrenal axis. It promotes liver glycogen deposition and thymus involution in adrenalectomized male rats, highlighting its physiological relevance. Additionally, Win 45164 exhibits significant anti-inflammatory properties, making it a valuable tool for research in inflammatory and neurological diseases.
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