Product Data Sheet
SNX281
Catalog No. A64843
SNX281 is a selective STING agonist that functions by inducing homodimerization at the STING binding site, leading to a conformational shift that activates STING and initiates downstream signaling pathways. This compound effectively stimulates the production of type I interferons, including IFN-β, as well as TNF-α and IL-6, resulting in enhanced T cell responses and prolonged immune memory. SNX281 demonstrates anti-tumor activity and is valuable for research applications in colorectal cancer, melanoma, advanced solid tumors, lymphoma, and ovarian cancer.
Chemical Information
| Catalog Num | A64843 |
|---|---|
| M. Wt | 389.90 |
| Formula | C20H20ClNO3S |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 2332803-84-4 |
| Synonyms | |
| SMILES | O=C(CN1C2=CC(C(C)(C)C)=CC=C2C(C3=CC=C(C(SC)=C31)Cl)=O)O |
Biological Activity
| Description | SNX281 is a selective STING agonist that functions by inducing homodimerization at the STING binding site, leading to a conformational shift that activates STING and initiates downstream signaling pathways. This compound effectively stimulates the production of type I interferons, including IFN-β, as well as TNF-α and IL-6, resulting in enhanced T cell responses and prolonged immune memory. SNX281 demonstrates anti-tumor activity and is valuable for research applications in colorectal cancer, melanoma, advanced solid tumors, lymphoma, and ovarian cancer. |
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RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
