Product Data Sheet
cAIMP
Catalog No. A64866
cAIMP (Cyclic Adenosine-Inosine Monophosphate) functions as a synthetic cyclic dinucleotide that activates immune response pathways by engaging IRF and NF-κB in the THP1 human monocyte reporter cell line (THP1-Dual). This compound is capable of inducing the secretion of interferons and pro-inflammatory cytokines in vitro in human blood, demonstrating an EC50 of 6.4 μmol/L. cAIMP serves as a valuable tool for research focused on innate immune signaling and inflammation responses.
Chemical Information
| Catalog Num | A64866 |
|---|---|
| M. Wt | 659.40 |
| Formula | C20H23N9O13P2 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 1507367-51-2 |
| Synonyms | Cyclic Adenosine-Inosine Monophosphate |
| SMILES | O[C@H]1[C@@H](O[C@@]2([H])[C@@]1([H])OP(O)(OC[C@]3([H])[C@@]([C@H]([C@H](N4C5=C(C(N=CN5)=O)N=C4)O3)O)([H])OP(O)(OC2)=O)=O)N6C7=NC=NC(N)=C7N=C6 |
Biological Activity
| Description | cAIMP (Cyclic Adenosine-Inosine Monophosphate) functions as a synthetic cyclic dinucleotide that activates immune response pathways by engaging IRF and NF-κB in the THP1 human monocyte reporter cell line (THP1-Dual). This compound is capable of inducing the secretion of interferons and pro-inflammatory cytokines in vitro in human blood, demonstrating an EC50 of 6.4 μmol/L. cAIMP serves as a valuable tool for research focused on innate immune signaling and inflammation responses. |
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RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
