Product Data Sheet
WT1 126-134 peptide
Catalog No. A65030
WT1 126-134 peptide is a peptide derived from the Wilms' tumor oncogene protein (RMFPNAPYL) that targets HLA-A0201. This peptide is known to induce cytotoxic CD8 T cells, which are capable of identifying and eliminating WT1-positive tumor cells. Additionally, WT1 126-134 peptide forms highly stable complexes with H-2Db (mouse) or HLA-A0201 (human), demonstrating a strong affinity (Kd = 0.2 nM) for humanized monoclonal antibodies (IgG1). It is applicable in immunotherapy as a vaccine for T cell activation or as a target for antibody development.
Chemical Information
| Catalog Num | A65030 |
|---|---|
| M. Wt | 1108.31 |
| Formula | C52H77N13O12S |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 256952-63-3 |
| Synonyms | |
| SMILES | C([C@H](CC1=CC=CC=C1)NC([C@@H](NC([C@H](CCCNC(=N)N)N)=O)CCSC)=O)(=O)N2[C@H](C(N[C@H](C(N[C@H](C(=O)N3[C@H](C(N[C@@H](CC4=CC=C(O)C=C4)C(N[C@@H](CC(C)C)C(O)=O)=O)=O)CCC3)C)=O)CC(N)=O)=O)CCC2 |
Biological Activity
| Description | WT1 126-134 peptide is a peptide derived from the Wilms' tumor oncogene protein (RMFPNAPYL) that targets HLA-A0201. This peptide is known to induce cytotoxic CD8 T cells, which are capable of identifying and eliminating WT1-positive tumor cells. Additionally, WT1 126-134 peptide forms highly stable complexes with H-2Db (mouse) or HLA-A0201 (human), demonstrating a strong affinity (Kd = 0.2 nM) for humanized monoclonal antibodies (IgG1). It is applicable in immunotherapy as a vaccine for T cell activation or as a target for antibody development. |
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RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
