Product Data Sheet
TP53 neoepitope
Catalog No. A65041
TP53 neoepitope is a high-affinity antigenic peptide that targets HLA-A molecules. It is designed to elicit CD8+ T cell-mediated cytotoxicity against tumor cells harboring TP53 mutations, specifically hotspot mutations such as R175H and R273H. This peptide is promising for research applications in the immunotherapy of solid tumors with TP53 alterations, providing insights into potential therapeutic interventions targeting mutant TP53 pathways.
Chemical Information
| Catalog Num | A65041 |
|---|---|
| M. Wt | 1111.30 |
| Formula | C45H74N16O13S2 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 151808-74-1 |
| Synonyms | |
| SMILES | [C@@H](CC1=CN=CN1)(NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@H](CC2=CN=CN2)N)=O)CCSC)=O)[C@@H](C)O)=O)CCC(O)=O)=O)C(C)C)=O)[C@@H](C)C)=O)CCCNC(=N)N)=O)C(N[C@H](C(O)=O)CS)=O |
Biological Activity
| Description | TP53 neoepitope is a high-affinity antigenic peptide that targets HLA-A molecules. It is designed to elicit CD8+ T cell-mediated cytotoxicity against tumor cells harboring TP53 mutations, specifically hotspot mutations such as R175H and R273H. This peptide is promising for research applications in the immunotherapy of solid tumors with TP53 alterations, providing insights into potential therapeutic interventions targeting mutant TP53 pathways. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
