Product Data Sheet
Ferroheme
Catalog No. A65064
Ferroheme is the ferrous form of heme that functions primarily as an oxygen carrier through reversible oxygen binding. Its free form is known to induce oxidative stress and ferroptosis by releasing iron ions, which facilitate the generation of reactive oxygen species via Fenton reactions. This mechanism plays a significant role in pathological conditions such as intracerebral hemorrhage and neurodegenerative diseases, making Ferroheme a valuable reagent for research into iron-overload disorders and the mechanisms underlying ferroptosis-related pathologies.
Chemical Information
| Catalog Num | A65064 |
|---|---|
| M. Wt | 616.49 |
| Formula | C34H32FeN4O4 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 14875-96-8 |
| Synonyms | |
| SMILES | [O-]C(CCC(C1=CC(C(CCC([O-])=O)=C2C)=[N](C2=C3)[Fe+2]4([N-]5C3=C6C)[N-]1C7=CC(C(C=C)=C8C)=[N]4C8=CC5=C6C=C)=C7C)=O.[H+].[H+] |
Biological Activity
| Description | Ferroheme is the ferrous form of heme that functions primarily as an oxygen carrier through reversible oxygen binding. Its free form is known to induce oxidative stress and ferroptosis by releasing iron ions, which facilitate the generation of reactive oxygen species via Fenton reactions. This mechanism plays a significant role in pathological conditions such as intracerebral hemorrhage and neurodegenerative diseases, making Ferroheme a valuable reagent for research into iron-overload disorders and the mechanisms underlying ferroptosis-related pathologies. |
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RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
