Product Data Sheet
NG-nitro-L-arginine
Catalog No. A65088
NG-nitro-L-arginine is a potent nitric oxide synthase (NOS) inhibitor, demonstrating inhibitory constants (Kis) of 0.61 μM for neuronal NOS (nNOS), 4.28 μM for inducible NOS (iNOS), and 0.72 μM for endothelial NOS (eNOS). This compound effectively inhibits the formation and release of endothelium-derived relaxing factor (EDRF), making it a valuable tool in cardiovascular research. NG-nitro-L-arginine has been shown to reduce portal-systemic shunting in portal-hypertensive rat models and is associated with increased blood pressure, thereby serving as a key reagent for studies investigating vascular function and regulation.
Chemical Information
| Catalog Num | A65088 |
|---|---|
| M. Wt | 219.20 |
| Formula | C6H13N5O4 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 2149-70-4 |
| Synonyms | Nω-nitro-L-arginine; L-NOARG; L-NG-Nitroarginine |
| SMILES | N[C@@H](CCCNC(N[N+]([O-])=O)=N)C(O)=O |
Biological Activity
| Description | NG-nitro-L-arginine is a potent nitric oxide synthase (NOS) inhibitor, demonstrating inhibitory constants (Kis) of 0.61 μM for neuronal NOS (nNOS), 4.28 μM for inducible NOS (iNOS), and 0.72 μM for endothelial NOS (eNOS). This compound effectively inhibits the formation and release of endothelium-derived relaxing factor (EDRF), making it a valuable tool in cardiovascular research. NG-nitro-L-arginine has been shown to reduce portal-systemic shunting in portal-hypertensive rat models and is associated with increased blood pressure, thereby serving as a key reagent for studies investigating vascular function and regulation. |
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RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
