Aminopicoline
Catalog No. A65093

Aminopicoline is a potent and non-selective inhibitor of nitric oxide synthase (NOS) isoenzymes, including iNOS, nNOS, and eNOS. By competing with arginine at the substrate-binding site, it effectively reduces cellular nitric oxide production and inhibits the elevation of plasma nitrate levels, which can influence mean arterial pressure. This compound serves as a valuable tool in research focused on diseases related to septic shock, joint and intestinal inflammation, as well as central nervous system (CNS) inflammation.
Chemical Information
| Catalog Num | A65093 |
|---|---|
| M. Wt | 108.14 |
| Formula | C6H8N2 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 695-34-1 |
| Synonyms | Ascensil; 2-Amino-4-methylpyridine |
| SMILES | NC1=NC=CC(C)=C1 |
Biological Activity
| Description | Aminopicoline is a potent and non-selective inhibitor of nitric oxide synthase (NOS) isoenzymes, including iNOS, nNOS, and eNOS. By competing with arginine at the substrate-binding site, it effectively reduces cellular nitric oxide production and inhibits the elevation of plasma nitrate levels, which can influence mean arterial pressure. This compound serves as a valuable tool in research focused on diseases related to septic shock, joint and intestinal inflammation, as well as central nervous system (CNS) inflammation. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.


