Product Data Sheet
TRIM
Catalog No. A65110
TRIM is a potent nitric oxide synthase (NOS) inhibitor, selectively targeting neuronal nitric oxide synthase (nNOS) in mouse cerebellar samples and inducible nitric oxide synthase (iNOS) in rat lung tissues, with IC50 values of 28.2 µM and 27.0 µM, respectively. This compound exhibits significant antidepressant and anxiolytic-like properties, making it valuable for research into depression and anxiety disorders. TRIM serves as an important tool for investigations into NOS-related pathways and their implications in neuropsychiatric conditions.
Chemical Information
| Catalog Num | A65110 |
|---|---|
| M. Wt | 212.17 |
| Formula | C10H7F3N2 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 25371-96-4 |
| Synonyms | |
| SMILES | FC(C1=CC=CC=C1N2C=CN=C2)(F)F |
Biological Activity
| Description | TRIM is a potent nitric oxide synthase (NOS) inhibitor, selectively targeting neuronal nitric oxide synthase (nNOS) in mouse cerebellar samples and inducible nitric oxide synthase (iNOS) in rat lung tissues, with IC50 values of 28.2 µM and 27.0 µM, respectively. This compound exhibits significant antidepressant and anxiolytic-like properties, making it valuable for research into depression and anxiety disorders. TRIM serves as an important tool for investigations into NOS-related pathways and their implications in neuropsychiatric conditions. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
