Product Data Sheet
1,4-PBIT dihydrobromide
Catalog No. A65118
1,4-PBIT dihydrobromide is a potent inhibitor of nitric oxide synthases (NOS), demonstrating Ki values of 7.6 nM for inducible NOS (iNOS), 360 nM for endothelial NOS (eNOS), and 16 nM for neuronal NOS (nNOS). This compound serves as a valuable tool for investigating nitric oxide signaling pathways and assessing the role of NOS in various biological contexts. It is applicable in studies related to inflammation, neurobiology, and cardiovascular research.
Chemical Information
| Catalog Num | A65118 |
|---|---|
| M. Wt | 444.25 |
| Formula | C12H20Br2N4S2 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 157254-60-9 |
| Synonyms | 1,4-PB-ITU dihydrobromide |
| SMILES | NC(SCCC1=CC=C(CCSC(N)=N)C=C1)=N.[H]Br.[H]Br |
Biological Activity
| Description | 1,4-PBIT dihydrobromide is a potent inhibitor of nitric oxide synthases (NOS), demonstrating Ki values of 7.6 nM for inducible NOS (iNOS), 360 nM for endothelial NOS (eNOS), and 16 nM for neuronal NOS (nNOS). This compound serves as a valuable tool for investigating nitric oxide signaling pathways and assessing the role of NOS in various biological contexts. It is applicable in studies related to inflammation, neurobiology, and cardiovascular research. |
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RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
