Product Data Sheet

Curvularin

Catalog No. A65123

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Curvularin is a potent inhibitor of inducible nitric oxide synthase (iNOS), demonstrating a half-maximal inhibitory concentration (IC50) of 9.5 µM. Isolated from the fungus Curvularia lunata, this mycotoxin is utilized in research to explore its effects on nitric oxide production in inflammatory responses. Curvularin's unique properties make it a valuable tool for investigating various biological processes and therapeutic applications related to iNOS inhibition.
Chemical Information
Catalog NumA65123
M. Wt292.33
FormulaC16H20O5
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.10140-70-2
Synonyms(S)-Curvularin
SMILESO=C(O[C@@H](C)CCCCC1)CC2=CC(O)=CC(O)=C2C1=O
Biological Activity
DescriptionCurvularin is a potent inhibitor of inducible nitric oxide synthase (iNOS), demonstrating a half-maximal inhibitory concentration (IC50) of 9.5 µM. Isolated from the fungus Curvularia lunata, this mycotoxin is utilized in research to explore its effects on nitric oxide production in inflammatory responses. Curvularin's unique properties make it a valuable tool for investigating various biological processes and therapeutic applications related to iNOS inhibition.
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