Product Data Sheet
Bacoside A
Catalog No. A65137
Bacoside A is an anti-apoptotic triterpenoid saponin derived from Bacopa monnieri, known for its ability to penetrate the blood-brain barrier. It exhibits significant antioxidant, anti-inflammatory, and neuroprotective properties by modulating the activities of ATPases, AChE, CaMK2A, and iNOS. Bacoside A helps maintain ion balance, scavenges reactive oxygen species, and regulates NF-κB and apoptosis-related proteins, thereby protecting nerve cells from stress-induced damage and exerting non-apoptotic cytotoxicity against glioblastoma cells. Its applications extend to research in neurological disorders, including Parkinson's disease and glioblastoma multiforme.
Chemical Information
| Catalog Num | A65137 |
|---|---|
| M. Wt | 768.97 |
| Formula | C41H68O13 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 11028-00-5 |
| Synonyms | |
| SMILES | C/C(C)=C\CC[C@@]([C@@H]1[C@H]2CC[C@H]3[C@](CC[C@@H]4[C@]3(CO)CCC(O[C@H]5[C@H](O)[C@@H](O)[C@H](O[C@H]6[C@H](O)[C@@H](O)[C@@H](O)CO6)[C@@H](CO)O5)C4(C)C)(C)[C@]2(C)CC1=O)(O)C |
Biological Activity
| Description | Bacoside A is an anti-apoptotic triterpenoid saponin derived from Bacopa monnieri, known for its ability to penetrate the blood-brain barrier. It exhibits significant antioxidant, anti-inflammatory, and neuroprotective properties by modulating the activities of ATPases, AChE, CaMK2A, and iNOS. Bacoside A helps maintain ion balance, scavenges reactive oxygen species, and regulates NF-κB and apoptosis-related proteins, thereby protecting nerve cells from stress-induced damage and exerting non-apoptotic cytotoxicity against glioblastoma cells. Its applications extend to research in neurological disorders, including Parkinson's disease and glioblastoma multiforme. |
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RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
