Product Data Sheet

hDDAH-1-IN-1 TFA

Catalog No. A65149

main product photo
hDDAH-1-IN-1 TFA is a selective non-amino acid inhibitor targeting human dimethylarginine dimethylaminohydrolase-1 (hDDAH-1), exhibiting a Ki of 18 μM. This compound demonstrates potent inhibition of the enzyme's catalytic activity, making it a valuable tool for studying the regulation of nitric oxide synthase and the metabolism of asymmetric dimethylarginines. Research applications include investigations into cardiovascular diseases, endothelial function, and polyamine metabolism.
Chemical Information
Catalog NumA65149
M. Wt416.32
FormulaC12H22F6N4O5
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.1229238-70-3
Synonyms
SMILESN=C(NCCOC)NCCCCN.O=C(O)C(F)(F)F.O=C(O)C(F)(F)F
Biological Activity
DescriptionhDDAH-1-IN-1 TFA is a selective non-amino acid inhibitor targeting human dimethylarginine dimethylaminohydrolase-1 (hDDAH-1), exhibiting a Ki of 18 μM. This compound demonstrates potent inhibition of the enzyme's catalytic activity, making it a valuable tool for studying the regulation of nitric oxide synthase and the metabolism of asymmetric dimethylarginines. Research applications include investigations into cardiovascular diseases, endothelial function, and polyamine metabolism.
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