Product Data Sheet
3,4-DAA
Catalog No. A65157
3,4-DAA is an orally active anthranilic acid derivative that acts as an immunosuppressive agent. It effectively mitigates colitis severity by inhibiting Th1 cell responses and promoting the expression of Th2 cytokines, as well as inducing CD4+CD25+ T cell expression. Additionally, 3,4-DAA reduces the expression of inducible nitric oxide synthase (iNOS) and the release of nitric oxide (NO) from EOC20 cells stimulated by IFN-γ and lipopolysaccharide. This makes it a valuable tool for research in immunology and inflammatory diseases.
Chemical Information
| Catalog Num | A65157 |
|---|---|
| M. Wt | 343.33 |
| Formula | C18H17NO6 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 2117759-07-4 |
| Synonyms | |
| SMILES | O=C(C1=C(NC(/C=C/C2=CC=C(C(OC)=C2)OC)=O)C(O)=CC=C1)O |
Biological Activity
| Description | 3,4-DAA is an orally active anthranilic acid derivative that acts as an immunosuppressive agent. It effectively mitigates colitis severity by inhibiting Th1 cell responses and promoting the expression of Th2 cytokines, as well as inducing CD4+CD25+ T cell expression. Additionally, 3,4-DAA reduces the expression of inducible nitric oxide synthase (iNOS) and the release of nitric oxide (NO) from EOC20 cells stimulated by IFN-γ and lipopolysaccharide. This makes it a valuable tool for research in immunology and inflammatory diseases. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
