Product Data Sheet
YIGSR-Lys(N3)
Catalog No. A65213
YIGSR-Lys(N3) is an antitumor peptide that targets cellular interactions with laminin I through the inhibition of the 67-kDa laminin-binding protein, effectively hindering the growth and metastasis of leukemic cells. Additionally, it modulates the shear-induced expression of endothelial nitric oxide synthase in laminin cells. This compound serves as a click chemistry reagent, featuring an azide group that participates in copper-catalyzed azide-alkyne cycloaddition and strain-promoted alkyne-azide cycloaddition reactions with alkyne-containing or DBCO/BCN-bearing molecules, respectively. Its versatile reactivity makes it valuable for research in both cancer biology and chemical biology applications.
Chemical Information
| Catalog Num | A65213 |
|---|---|
| M. Wt | 748.83 |
| Formula | C32H52N12O9 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 2415188-59-7 |
| Synonyms | |
| SMILES | [C@@H](NC([C@@H](NC(CNC([C@@H](NC([C@H](CC1=CC=C(O)C=C1)N)=O)[C@H](CC)C)=O)=O)CO)=O)(C(N[C@@H](CCCCN=[N+]=[N-])C(O)=O)=O)CCCNC(=N)N |
Biological Activity
| Description | YIGSR-Lys(N3) is an antitumor peptide that targets cellular interactions with laminin I through the inhibition of the 67-kDa laminin-binding protein, effectively hindering the growth and metastasis of leukemic cells. Additionally, it modulates the shear-induced expression of endothelial nitric oxide synthase in laminin cells. This compound serves as a click chemistry reagent, featuring an azide group that participates in copper-catalyzed azide-alkyne cycloaddition and strain-promoted alkyne-azide cycloaddition reactions with alkyne-containing or DBCO/BCN-bearing molecules, respectively. Its versatile reactivity makes it valuable for research in both cancer biology and chemical biology applications. |
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RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
