HTS13286
Catalog No. A65253

HTS13286 is a selective inhibitor of aquaporin 9 (AQP9), targeting water and glycerol transport in cells. This compound effectively attenuates lipopolysaccharide (LPS)-induced nitric oxide (NO) production and reduces glucose output in response to inflammatory stimuli. HTS13286 is valuable for research applications related to endotoxin shock and the study of metabolic dysregulation in inflammatory conditions.
Chemical Information
| Catalog Num | A65253 |
|---|---|
| M. Wt | 415.52 |
| Formula | C16H13N7OS3 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 727359-12-8 |
| Synonyms | |
| SMILES | O=C(CSC1=NN=C(N1C)C2=CC=NC=C2)NC3=NN=C(C4=CC=CS4)S3 |
Biological Activity
| Description | HTS13286 is a selective inhibitor of aquaporin 9 (AQP9), targeting water and glycerol transport in cells. This compound effectively attenuates lipopolysaccharide (LPS)-induced nitric oxide (NO) production and reduces glucose output in response to inflammatory stimuli. HTS13286 is valuable for research applications related to endotoxin shock and the study of metabolic dysregulation in inflammatory conditions. |
|---|
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Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.


