Product Data Sheet
L-NAME
Catalog No. A65259
L-NAME is a nitric oxide synthase (NOS) inhibitor with an IC50 of 70 μM. This compound acts as a precursor to the more potent NOS inhibitor L-NOARG, which has an IC50 of 1.4 μM. L-NAME requires hydrolysis by cellular esterases to achieve its full inhibitory activity. It is commonly utilized in research to induce hypertension and preeclampsia models, facilitating studies on cardiovascular health and nitric oxide signaling pathways.
Chemical Information
| Catalog Num | A65259 |
|---|---|
| M. Wt | 233.23 |
| Formula | C7H15N5O4 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 50903-99-6 |
| Synonyms | NG-Nitroarginine methyl ester |
| SMILES | N[C@@H](CCCNC(N[N+]([O-])=O)=N)C(OC)=O |
Biological Activity
| Description | L-NAME is a nitric oxide synthase (NOS) inhibitor with an IC50 of 70 μM. This compound acts as a precursor to the more potent NOS inhibitor L-NOARG, which has an IC50 of 1.4 μM. L-NAME requires hydrolysis by cellular esterases to achieve its full inhibitory activity. It is commonly utilized in research to induce hypertension and preeclampsia models, facilitating studies on cardiovascular health and nitric oxide signaling pathways. |
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RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
