Product Data Sheet
Stephalonine P
Catalog No. A65260
Stephalonine P is a hasubanan-type alkaloid that serves as a neuroinflammation inhibitor. It exhibits significant anti-inflammatory properties by inhibiting nitric oxide production in lipopolysaccharide-activated BV2 microglia, with an IC50 value of 34.01 μM. By reducing microglial activation, Stephalonine P provides neuroprotective effects, which are particularly relevant in the context of stroke and other neuroinflammation-related diseases. This compound can be isolated from the plant Stephania japonica and is valuable for research into neuroinflammatory mechanisms and therapeutic interventions.
Chemical Information
| Catalog Num | A65260 |
|---|---|
| M. Wt | 521.60 |
| Formula | C30H35NO7 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 2376309-57-6 |
| Synonyms | |
| SMILES | CO[C@@]12[C@]34[C@@](C[C@H]([C@H]2OC)OC(/C=C/C5=CC=CC=C5)=O)(CCN4C)C6=C(OC)C(OC)=CC=C6[C@@](O1)([H])C3 |
Biological Activity
| Description | Stephalonine P is a hasubanan-type alkaloid that serves as a neuroinflammation inhibitor. It exhibits significant anti-inflammatory properties by inhibiting nitric oxide production in lipopolysaccharide-activated BV2 microglia, with an IC50 value of 34.01 μM. By reducing microglial activation, Stephalonine P provides neuroprotective effects, which are particularly relevant in the context of stroke and other neuroinflammation-related diseases. This compound can be isolated from the plant Stephania japonica and is valuable for research into neuroinflammatory mechanisms and therapeutic interventions. |
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RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
