Product Data Sheet

SDMA (p-hydroxyazobenzene-p′-sulfonate)

Catalog No. A65271

main product photo
SDMA (p-hydroxyazobenzene-p′-sulfonate) is a potent endogenous inhibitor of nitric oxide synthase (NOS), making it a valuable tool for studying NOS-related pathways. This compound has been shown to activate NF-κB, leading to increased expression of pro-inflammatory cytokines such as IL-6 and TNF-α. Additionally, SDMA demonstrates stability in serum and plasma, allowing its use as a biomarker for assessing hepatic and renal dysfunction in various research applications.
Chemical Information
Catalog NumA65271
M. Wt378.41
FormulaC12H10N2O4S·1/2C8H18N4O2
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.1266235-58-8
SynonymsSymmetric dimethylarginine (p-hydroxyazobenzene-p′-sulfonate); NG,NG'-Dimethyl-L-arginine (p-hydroxyazobenzene-p′-sulfonate)
SMILESOC(C=C1)=CC=C1/N=N/C2=CC=C(C=C2)S(=O)(O)=O.OC([C@@H](N)CCC/N=C(NC)/NC)=O.[0.5]
Biological Activity
DescriptionSDMA (p-hydroxyazobenzene-p′-sulfonate) is a potent endogenous inhibitor of nitric oxide synthase (NOS), making it a valuable tool for studying NOS-related pathways. This compound has been shown to activate NF-κB, leading to increased expression of pro-inflammatory cytokines such as IL-6 and TNF-α. Additionally, SDMA demonstrates stability in serum and plasma, allowing its use as a biomarker for assessing hepatic and renal dysfunction in various research applications.
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SHIPPING AND STORAGE
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