Product Data Sheet
NOS-IN-3
Catalog No. A65308
NOS-IN-3 is a selective inhibitor of nitric oxide synthase (NOS) with a notable affinity for inducible nitric oxide synthase (iNOS), exhibiting an IC50 of 4.6 μM, while sparing endothelial nitric oxide synthase (eNOS). This compound demonstrates minimal toxicity, making it suitable for investigations into diseases associated with the inducible isoform, such as septic shock. NOS-IN-3 is a valuable tool for elucidating the role of iNOS in various pathological conditions.
Chemical Information
| Catalog Num | A65308 |
|---|---|
| M. Wt | 193.25 |
| Formula | C10H15N3O |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 2761725-68-0 |
| Synonyms | |
| SMILES | CC(NCCC(C1=CC=CN=C1)O)=N |
Biological Activity
| Description | NOS-IN-3 is a selective inhibitor of nitric oxide synthase (NOS) with a notable affinity for inducible nitric oxide synthase (iNOS), exhibiting an IC50 of 4.6 μM, while sparing endothelial nitric oxide synthase (eNOS). This compound demonstrates minimal toxicity, making it suitable for investigations into diseases associated with the inducible isoform, such as septic shock. NOS-IN-3 is a valuable tool for elucidating the role of iNOS in various pathological conditions. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
