Product Data Sheet
L-NAPNA
Catalog No. A65323
L-NAPNA is a selective nitric oxide synthase (NOS) inhibitor, demonstrated to have an IC50 of 1.4 μM. It exhibits significant analgesic effects, as evidenced by its ability to reduce formalin-induced paw licking behavior in mice (ED50 of 57.2 mg/kg) and diminish acetic acid-induced abdominal writhing (ED50 of 25 mg/kg). This compound is valuable for exploring therapeutic approaches in research focused on central nervous system disorders.
Chemical Information
| Catalog Num | A65323 |
|---|---|
| M. Wt | 339.31 |
| Formula | C12H17N7O5 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 85697-89-8 |
| Synonyms | |
| SMILES | O=C(NC1=CC=C([N+]([O-])=O)C=C1)[C@@H](N)CCCNC(N[N+]([O-])=O)=N |
Biological Activity
| Description | L-NAPNA is a selective nitric oxide synthase (NOS) inhibitor, demonstrated to have an IC50 of 1.4 μM. It exhibits significant analgesic effects, as evidenced by its ability to reduce formalin-induced paw licking behavior in mice (ED50 of 57.2 mg/kg) and diminish acetic acid-induced abdominal writhing (ED50 of 25 mg/kg). This compound is valuable for exploring therapeutic approaches in research focused on central nervous system disorders. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
