Product Data Sheet
PSB-06126
Catalog No. A65351
PSB-06126 is a selective inhibitor of nucleoside triphosphate diphosphohydrolase (NTPDase), demonstrating Ki values of 0.33 μM for rat NTPDase 1, 19.1 μM for NTPDase 2, and 2.22 μM for NTPDase 3. In human NTPDase 3, it exhibits an IC50 value of 7.76 μM and a Ki value of 4.39 μM. This compound is useful for studying the role of NTPDases in purinergic signaling and may aid in the exploration of therapeutic strategies targeting related pathological conditions.
Chemical Information
| Catalog Num | A65351 |
|---|---|
| M. Wt | 466.44 |
| Formula | C24H15N2NaO5S |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 1052089-16-3 |
| Synonyms | |
| SMILES | O=S(C(C(N)=C1C2=O)=CC(NC3=C4C=CC=CC4=CC=C3)=C1C(C5=C2C=CC=C5)=O)(O[Na])=O |
Biological Activity
| Description | PSB-06126 is a selective inhibitor of nucleoside triphosphate diphosphohydrolase (NTPDase), demonstrating Ki values of 0.33 μM for rat NTPDase 1, 19.1 μM for NTPDase 2, and 2.22 μM for NTPDase 3. In human NTPDase 3, it exhibits an IC50 value of 7.76 μM and a Ki value of 4.39 μM. This compound is useful for studying the role of NTPDases in purinergic signaling and may aid in the exploration of therapeutic strategies targeting related pathological conditions. |
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RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
